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基質(zhì)蛋白M1(58-66)(甲型流感病毒)

NMR下載 COA and HPLC MSDS下載
names：
CEF1, Influenza Matrix Protein M1 58-66
CAS號：
141368-69-6
MDL Number：
MF(分子式)： C49H75N9O11 MW(分子量)： 966.17
EINECS: Reaxys Number:
Pubchem ID:446076 Brand:BIOFOUNT

基質(zhì)蛋白M1(58-66)(甲型流感病毒)CEF1, Influenza Matrix Protein M1 58-66(141368-69-6)是源自甲型流感病毒基質(zhì)蛋白的表位。

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YZM000746-5mg	5mg		￥ 0.00	￥ 0.00		Backorder	- +	￥ 0.00
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中文別名	基質(zhì)蛋白M1(58-66)(甲型流感病毒)(141368-69-6);CEF1，流感基質(zhì)蛋白M1（58-66）;基質(zhì)蛋白M1（58-66）（甲型流感病毒）;CHEMBL1869460;HY-P0137;ZINC150355093;NCGC00167248-01;CS-0019779;基質(zhì)蛋白M1（58-66）（甲型流感病毒);基質(zhì)蛋白M1（58-66）（流感病毒）；H-甘氨酸-ILE-LEU-GLY-PHE-VAL-PHE-THR-LEU-OH; H2N-GILGFVFTL-OH；GLY-ILE-LEU-GLY-PHE-VAL-PHE-THR-LEU 流感基質(zhì)肽; INFLUENZA MATRIX蛋白質(zhì)M1（58-66）；流感病毒基質(zhì)蛋白（58-66）; GILGFVFTL;
英文別名	CEF1, Influenza Matrix Protein M1 58-66(141368-69-6); CEF1, Influenza Matrix Protein M1 (58-66);Matrix Protein M1 (58-66) (Influenza A virus);CHEMBL1869460;HY-P0137;ZINC150355093;NCGC00167248-01;CS-0019779;Matrix protein m1(58-66)(influenza a virus); MATRIX PROTEIN M1 (58-66) (INFLUENZA A VIRUS); H-GLY-ILE-LEU-GLY-PHE-VAL-PHE-THR-LEU-OH; H2N-GILGFVFTL-OH; GLY-ILE-LEU-GLY-PHE-VAL-PHE-THR-LEU; INFLUENZA MATRIX PEPTIDE; INFLUENZA MATRIX PROTEIN M1 (58-66); INFLUENZA VIRUS MATRIX PROTEIN (58-66); GILGFVFTL;
CAS號	141368-69-6
Inchi	InChI=1S/C49H75N9O11/c1-10-30(8)41(56-38(60)25-50)47(66)53-34(21-27(2)3)43(62)51-26-39(61)52-35(23-32-17-13-11-14-18-32)44(63)57-40(29(6)7)46(65)54-36(24-33-19-15-12-16-20-33)45(64)58-42(31(9)59)48(67)55-37(49(68)69)22-28(4)5/h11-20,27-31,34-37,40-42,59H,10,21-26,50H2,1-9H3,(H,51,62)(H,52,61)(H,53,66)(H,54,65)(H,55,67)(H,56,60)(H,57,63)(H,58,64)(H,68,69)/t30-,31+,34-,35-,36-,37-,40-,41-,42-/m0/s1
InchiKey	NBDRFCQNHCTWII-CXECYRLYSA-N
分子式 Formula	C49H75N9O11
分子量 Molecular Weight	966.17
溶解度Solubility
性狀	Solid
儲藏條件 Storage conditions	請根據(jù)產(chǎn)品建議的存儲條件進(jìn)行存儲,Please store the product under the recommended condition sin the description.

基質(zhì)蛋白M1(58-66)(甲型流感病毒)CEF1, Influenza Matrix Protein M1 58-66(141368-69-6)實驗注意事項：
1.實驗前需戴好防護(hù)眼鏡，穿戴防護(hù)服和口罩，佩戴手套，避免與皮膚接觸。
2.實驗過程中如遇到有毒或者刺激性物質(zhì)及有害物質(zhì)產(chǎn)生，必要時實驗操作需要手套箱內(nèi)完成以免對實驗人員造成傷害
3.實驗后產(chǎn)生的廢棄物需分類存儲，并交于專業(yè)生物廢氣物處理公司處理，以免造成環(huán)境污染Experimental considerations:
1. Wear protective glasses, protective clothing and masks, gloves, and avoid contact with the skin during the experiment.
2. The waste generated after the experiment needs to be stored separately, and handed over to a professional biological waste gas treatment company to avoid environmental pollution.

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產(chǎn)品說明	基質(zhì)蛋白M1(58-66)(甲型流感病毒)CEF1, Influenza Matrix Protein M1 58-66(141368-69-6)是源自甲型流感病毒基質(zhì)蛋白的表位
Introduction	基質(zhì)蛋白M1(58-66)(甲型流感病毒)CEF1, Influenza Matrix Protein M1 58-66(141368-69-6) is an epitope derived from the matrix protein of the influenza A virus.
Application1
Application2
Application3

基質(zhì)蛋白M1(58-66)(甲型流感病毒)CEF1, Influenza Matrix Protein M1 58-66(141368-69-6)藥理學(xué)：

基質(zhì)蛋白M1(58-66)(甲型流感病毒)CEF1, Influenza Matrix Protein M1 58-66(141368-69-6)是源自甲型流感病毒基質(zhì)蛋白的表位。

警示圖
危險性	warning
危險性警示	Not available
安全聲明	H303吞入可能有害+H313皮膚接觸可能有害+H2413吸入可能對身體有害
安全防護(hù)	P264處理后徹底清洗+P280戴防護(hù)手套/穿防護(hù)服/戴防護(hù)眼罩/戴防護(hù)面具+P305如果進(jìn)入眼睛+P351用水小心沖洗幾分鐘+P338取出隱形眼鏡（如果有）并且易于操作,繼續(xù)沖洗+P337如果眼睛刺激持續(xù)+P2393獲得醫(yī)療建議/護(hù)理
備注	實驗過程中防止吸入、食入，做好安全防護(hù)

Petrova GV, et al. Cross-reactive responses to modified M1 peptides by CD8? T cells that use noncanonical BV genes can describe unknown repertoires. Eur J Immunol. 2012 Nov;42(11):3001-8.

基質(zhì)蛋白M1(58-66)(甲型流感病毒)CEF1, Influenza Matrix Protein M1 58-66(141368-69-6)參考文獻(xiàn)：

1、Cross-reactive responses to modified M1 peptides by CD8 T cells that use noncanonical BV genes can describe unknown repertoires
Galina V Petrova 1, Jack Gorski

Abstract Memory T-cell repertoires are populated by clonotypes selected by an individual's history of antigen exposures. Our previous analysis of middle-age CD8(+) T-cell memory repertoires to the influenza-derived epitope M1(58-66) , described a network of highly cross-reactive BV19 clonotypes responding to M1(58-66) and at least one peptide with a conservative amino acid substitution at either of two TCR contact positions. Here, we report that some substitutions abrogate BV19 responses and favor responses with different BV. Cross-reactive T cells using seven other BV families responded to 12 of 13 peptides tested. BV12 clonotypes define the most extensive cross-reactive network that encompasses seven peptides. We generated 3D networks based on the peptides recognized and BV family used and observed a cluster of five peptides that includes M1(58-66) and another cluster of five peptides that does not include M1(58-66) . The first cluster represents peptides structurally similar to M1(58-66) , and the second represents peptides with more considerable changes in epitope recognition surface. We hypothesize that the second cluster represents the cross-reactive network around another unknown epitope or epitopes. This data supports a model of stable CD8(+) T-cell memory networks that include a substantial contribution from cross-reactive T cells.

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