購物車 
-
Aspartyl adenylate
- names：
(9-((2R,3R,4S,5R)-3,4-dihydroxy-5-((phosphonooxy)methyl)tetrahydrofuran-2-yl)-9H-purin-6-yl)-L-aspartic acid
- CAS號：
19046-78-7
MDL Number： - MF(分子式)： C14H18N5O11P MW(分子量)： 463.29
- EINECS: Reaxys Number:
- Pubchem ID: Brand:BIOFOUNT
| 貨品編碼 | 規(guī)格 | 純度 | 價格 (￥) | 現(xiàn)價(￥) | 特價(￥) | 庫存描述 | 數(shù)量 | 總計 (￥) |
|---|
| 中文別名 | Aspartyl adenylate |
| 英文別名 | Aspartyl adenylate; |
| CAS號 | 19046-78-7 |
| Inchi | InChI=1S/C14H18N5O11P/c20-7(21)1-5(14(24)25)18-11-8-12(16-3-15-11)19(4-17-8)13-10(23)9(22)6(30-13)2-29-31(26,27)28/h3-6,9-10,13,22-23H,1-2H2,(H,20,21)(H,24,25)(H,15,16,18)(H2,26,27,28)/t5-,6+,9+,10+,13+/m0/s1 |
| InchiKey | OFBHPPMPBOJXRT-VWJPMABRSA-N |
| 分子式 Formula | C14H18N5O11P |
| 分子量 Molecular Weight | 463.29 |
| 溶解度Solubility | |
| 性狀 | Solid powder |
| 儲藏條件 Storage conditions | Dry, dark and store at 0-4℃ for short term (days to weeks) or -20℃ for long term (Store correctly 2-3years). |
| 產(chǎn)品說明 | Aspartyl adenylate(CAS:19046-78-7):僅限應(yīng)用于工業(yè)或者科學(xué)研究過程中非醫(yī)療目的，不應(yīng)用于人類或動物的臨床診斷以及治過程療，該產(chǎn)品非藥用，非食用。 |
| Introduction | Aspartyl adenylate is the adenyl derivative of succinic acid that plays a part in nucleotide metabolism. |
| Application1 | |
| Application2 | |
| Application3 |
| [1]Serebryakova M, Tsibulskaya D, Mokina O, Kulikovsky A, Nautiyal M, Van Aerschot A, Severinov K, Dubiley S. A Trojan-Horse Peptide-Carboxymethyl-Cytidine Antibiotic from Bacillus amyloliquefaciens. J Am Chem Soc. 2016 Dec 7;138(48):15690-15698. Epub 2016 Nov 29. PubMed PMID: 27934031; PubMed Central PMCID: PMC5152938. |
| [2]Kazakov T, Kuznedelov K, Semenova E, Mukhamedyarov D, Datsenko KA, Metlitskaya A, Vondenhoff GH, Tikhonov A, Agarwal V, Nair S, Van Aerschot A, Severinov K. The RimL transacetylase provides resistance to translation inhibitor microcin C. J Bacteriol. 2014 Oct;196(19):3377-85. doi: 10.1128/JB.01584-14. Epub 2014 Jul 7. PubMed PMID: 25002546; PubMed Central PMCID: PMC4187662. |
| [3] Bantysh O, Serebryakova M, Makarova KS, Dubiley S, Datsenko KA, Severinov K. Enzymatic synthesis of bioinformatically predicted microcin C-like compounds encoded by diverse bacteria. MBio. 2014 May 6;5(3):e01059-14. doi: 10.1128/mBio.01059-14. PubMed PMID: 24803518; PubMed Central PMCID: PMC4010828. |
| [4] Rebuffat S. Microcins in action: amazing defence strategies of Enterobacteria. Biochem Soc Trans. 2012 Dec 1;40(6):1456-62. doi: 10.1042/BST20120183. Review. PubMed PMID: 23176498. |
| [5] Gaudry A, Lorber B, Neuenfeldt A, Sauter C, Florentz C, Sissler M. Re-designed N-terminus enhances expression, solubility and crystallizability of mitochondrial protein. Protein Eng Des Sel. 2012 Sep;25(9):473-81. doi: 10.1093/protein/gzs046. Epub 2012 Aug 7. PubMed PMID: 22871419. |
6: Agarwal V, Tikhonov A, Metlitskaya A, Severinov K, Nair SK. Structure and function of a serine carboxypeptidase adapted for degradation of the protein synthesis antibiotic microcin C7. Proc Natl Acad Sci U S A. 2012 Mar 20;109(12):4425-30. doi: 10.1073/pnas.1114224109. Epub 2012 Mar 2. PubMed PMID: 22388748; PubMed Central PMCID: PMC3311384.7: Severinov K, Nair SK. Microcin C: biosynthesis and mechanisms of bacterial resistance. Future Microbiol. 2012 Feb;7(2):281-9. doi: 10.2217/fmb.11.148. Review. PubMed PMID: 22324995; PubMed Central PMCID: PMC3350762.8: Vondenhoff GH, Van Aerschot A. Microcin C: biosynthesis, mode of action, and potential as a lead in antibiotics development. Nucleosides Nucleotides Nucleic Acids. 2011 Jul-Aug;30(7-8):465-74. doi: 10.1080/15257770.2011.583972. PubMed PMID: 21888539.9: Vondenhoff GH, Dubiley S, Severinov K, Lescrinier E, Rozenski J, Van Aerschot A. Extended targeting potential and improved synthesis of Microcin C analogs as antibacterials. Bioorg Med Chem. 2011 Sep 15;19(18):5462-7. doi: 10.1016/j.bmc.2011.07.052. Epub 2011 Aug 3. PubMed PMID: 21855353.10: Polydorides S, Amara N, Aubard C, Plateau P, Simonson T, Archontis G. Computational protein design with a generalized Born solvent model: application to Asparaginyl-tRNA synthetase. Proteins. 2011 Dec;79(12):3448-68. doi: 10.1002/prot.23042. Epub 2011 May 11. PubMed PMID: 21563215.1
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