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Fezelol

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names：
2H-1-Benzopyran-2-one, 7-((1,4,4a,5,6,7,8,8a-octahydro-6-hydroxy-2,5,5,8a-tetramethyl-1-naphthalenyl)methoxy)-, (1R-(1alpha,4abeta,6alpha,8aalpha))-
CAS號(hào)：
51020-36-1
MDL Number：
MF(分子式)： C24H30O4 MW(分子量)： 382.5
EINECS: Reaxys Number:
Pubchem ID: Brand:BIOFOUNT

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中文別名	Fezelol
英文別名	Fezelol; Feselol; Moschatol
CAS號(hào)	51020-36-1
Inchi	InChI=1S/C24H30O4/c1-15-5-9-20-23(2,3)21(25)11-12-24(20,4)18(15)14-27-17-8-6-16-7-10-22(26)28-19(16)13-17/h5-8,10,13,18,20-21,25H,9,11-12,14H2,1-4H3/t18-,20-,21-,24+/m0/s1
InchiKey	MCTDXPDDZLFJHR-SODVOOIJSA-N
分子式 Formula	C24H30O4
分子量 Molecular Weight	382.5
溶解度Solubility
性狀	Solid powder
儲(chǔ)藏條件 Storage conditions	Dry, dark and store at 0-4℃ for short term (days to weeks) or -20℃ for long term (Store correctly 2-3years).

產(chǎn)品說(shuō)明	Fezelol(CAS:51020-36-1):僅限應(yīng)用于工業(yè)或者科學(xué)研究過(guò)程中非醫(yī)療目的，不應(yīng)用于人類或動(dòng)物的臨床診斷以及治過(guò)程療，該產(chǎn)品非藥用，非食用。
Introduction	Fezelol is a sesquiterpene coumarin isolated from the fruits of Ferula badrakema.
Application1
Application2
Application3

警示圖
危險(xiǎn)性	Warning
危險(xiǎn)性警示
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[1]Mollazadeh S, Matin MM, Bahrami AR, Iranshahi M, Behnam-Rassouli M, Rassouli FB, Neshati V. Feselol enhances the cytotoxicity and DNA damage induced by cisplatin in 5637 cells. Z Naturforsch C. 2011 Nov-Dec;66(11-12):555-6[1]PubMed PMID: 22351980.

[2]Mollazadeh S, Matin MM, Iranshahi M, Bahrami AR, Neshati V, Behnam-Rassouli F. The enhancement of vincristine cytotoxicity by combination with feselol. J Asian Nat Prod Res. 2010 Jul;12(7):569-75. doi: 10.1080/10286020.2010.485565. PubMed PMID: 20628935.

[3] Iranshahi M, Barthomeuf C, Bayet-Robert M, Chollet P, Davoodi D, Piacente S, Rezaee R, Sahebkar A. Drimane-Type Sesquiterpene Coumarins from Ferula gummosa Fruits Enhance Doxorubicin Uptake in Doxorubicin-Resistant Human Breast Cancer Cell Line. J Tradit Complement Med. 2014 Apr;4(2):118-25. doi: 10.4103/2225-4110.126181. PubMed PMID: 24860735; PubMed Central PMCID: PMC4003701.

[4] Oughlissi-Dehak K, Lawton P, Michalet S, Bayet C, Darbour N, Hadj-Mahammed M, Badjah-Hadj-Ahmed YA, Dijoux-Franca MG, Guilet D. Sesquiterpenes from aerial parts of Ferula vesceritensis. Phytochemistry. 2008 Jun;69(9):1933-8. doi: 10.1016/j.phytochem.2008.03.010. Epub 2008 May 14. PubMed PMID: 18485426.

[5] Amin A, Tuenter E, Cos P, Maes L, Exarchou V, Apers S, Pieters L. Antiprotozoal and Antiglycation Activities of Sesquiterpene Coumarins from Ferula narthex Exudate. Molecules. 2016 Sep 26;21(10). pii: E1287. PubMed PMID: 27681714; PubMed Central PMCID: PMC6274357.

6: Iranshahi M, Masullo M, Asili A, Hamedzadeh A, Jahanbin B, Festa M, Capasso A, Piacente S. Sesquiterpene coumarins from Ferula gumosa. J Nat Prod. 2010 Nov 29;73(11):1958-62. doi: 10.1021/np100487j. Epub 2010 Oct 20. PubMed PMID: 20961138.7: Li G, Li X, Cao L, Zhang L, Shen L, Zhu J, Wang J, Si J. Sesquiterpene coumarins from seeds of Ferula sinkiangensis. Fitoterapia. 2015 Jun;10

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