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Rioprostil

NMR下載 COA and HPLC MSDS下載
names：
(2R,3R,4R)-4-hydroxy-3-((E)-4-hydroxy-4-methyloct-1-en-1-yl)-2-(7-hydroxyheptyl)cyclopentan-1-one
CAS號(hào)：
77287-05-9
MDL Number：
MF(分子式)： C21H38O4 MW(分子量)： 354.53
EINECS: Reaxys Number:
Pubchem ID: Brand:BIOFOUNT

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中文別名	(2R,3R,4R)-4-hydroxy-3-((E)-4-hydroxy-4-methyloct-1-en-1-yl)-2-(7-hydroxyheptyl)cyclopentan-1-one
英文別名	Rioprostil; Rioprostilum; TR-4698; TR 4698; TR4698;
CAS號(hào)	77287-05-9
Inchi	InChI=1S/C21H38O4/c1-3-4-13-21(2,25)14-10-12-18-17(19(23)16-20(18)24)11-8-6-5-7-9-15-22/h10,12,17-18,20,22,24-25H,3-9,11,13-16H2,1-2H3/b12-10+/t17-,18-,20-,21?/m1/s1
InchiKey	SPOAFZKFCYREMW-FWYLUGOYSA-N
分子式 Formula	C21H38O4
分子量 Molecular Weight	354.53
溶解度Solubility
性狀	Solid powder
儲(chǔ)藏條件 Storage conditions	Dry, dark and store at 0-4℃ for short term (days to weeks) or -20℃ for long term (Store correctly 2-3years).

產(chǎn)品說(shuō)明	Rioprostil(CAS:77287-05-9):僅限應(yīng)用于工業(yè)或者科學(xué)研究過(guò)程中非醫(yī)療目的，不應(yīng)用于人類或動(dòng)物的臨床診斷以及治過(guò)程療，該產(chǎn)品非藥用，非食用。
Introduction	Rioprostil is a synthetic methylprostaglandin E1 analog that reduces gastric acid secretion and enhances the gastric mucus-bicarbonate barrier. It is effective in the therapy of gastric ulcers and gives significant protection against NSAID-induced gastric mucosal damage. The drug also prevents cyclosporin A-induced damage to endocrine and exocrine pancreatic secretions. It shows a low order of acute toxicity and there is no evidence of embryotoxicity, fetotoxicity, teratogenicity, or mutagenicity in animal studies.
Application1
Application2
Application3

警示圖
危險(xiǎn)性	Warning
危險(xiǎn)性警示
安全聲明
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[1]Cohen A, Tolman KG, Lewis GP, Brown S, van Horn A, McCormack GH, Simon DM. The antigastrolesive activity of rioprostil, a 16-methyl prostaglandin-E1 analogue in healthy volunteers. Scand J Gastroenterol Suppl. 1989;16

4:81-90; discussion 90-1. PubMed PMID: 2510286.

[3]Boucekkine T, Meknini B, Bitoun A, Prunièras F, Khedis A, de Lauture D, Rotenberg A, Molinie C, Roux M, Gauthier A, et al. Treatment of duodenal ulcer with rioprostil: a randomized multicentre double-blind study. Scand J Gastroenterol Suppl. 1989;16

[4]191-3. PubMed PMID: 2510266.

[5] Fischer S, Schweer H, Kraft H, Weber P. Pharmacokinetics of rioprostil in human plasma as assayed by combined capillary gas chromatography-negative ion chemical ionization mass spectrometry. Scand J Gastroenterol Suppl. 1989;16

4:59-61; discussion 61-2. PubMed PMID: 2510282.

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