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Talopeptin

NMR下載 COA and HPLC MSDS下載
names：
(hydroxy(((2S,3R,4R,5S,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)phosphoryl)-L-leucyl-L-tryptophan
CAS號：
84235-60-9
MDL Number：
MF(分子式)： C23H34N3O10P MW(分子量)： 543.5
EINECS: Reaxys Number:
Pubchem ID: Brand:BIOFOUNT

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中文別名	(hydroxy(((2S,3R,4R,5S,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)phosphoryl)-L-leucyl-L-tryptophan
英文別名	Talopeptin;
CAS號	84235-60-9
Inchi	InChI=1S/C23H34N3O10P/c1-11(2)8-16(26-37(33,34)36-23-20(29)19(28)18(27)12(3)35-23)21(30)25-17(22(31)32)9-13-10-24-15-7-5-4-6-14(13)15/h4-7,10-12,16-20,23-24,27-29H,8-9H2,1-3H3,(H,25,30)(H,31,32)(H2,26,33,34)/t12-,16-,17-,18+,19+,20+,23-/m0/s1
InchiKey	ZPHBZEQOLSRPAK-XVOJFHBISA-N
分子式 Formula	C23H34N3O10P
分子量 Molecular Weight	543.5
溶解度Solubility
性狀	Solid powder
儲藏條件 Storage conditions	Dry, dark and store at 0-4℃ for short term (days to weeks) or -20℃ for long term (Store correctly 2-3years).

產品說明	Talopeptin(CAS:84235-60-9):僅限應用于工業(yè)或者科學研究過程中非醫(yī)療目的，不應用于人類或動物的臨床診斷以及治過程療，該產品非藥用，非食用。
Introduction	Talopeptin is a specific inhibitor for thermolysin.
Application1
Application2
Application3

警示圖
危險性	Warning
危險性警示
安全聲明
安全防護
備注

[1]Kitagishi K, Hiromi K, Tokushige M. Binding between thermolysin and talopeptin (MKI) in which the tryptophan residue was converted into kynurenine. J Biochem. 1983 Apr;93(4):1045-54. PubMed PMID: 6863233.

[2]Kitagishi K, Hiromi K, Oda K, Murao S. Equilibrium study on the binding between thermolysin and Streptomyces metalloprotease inhibitor, talopeptin (MKI). J Biochem. 1983 Jan;93(1):47-53. PubMed PMID: 6341369.

[3] Kitagishi K, Hiromi K. Studies on the chemical modification of tryptophan residues in thermolysin and in talopeptin (MKI) with N-bromosuccinimide. J Biochem. 1983 Jul;94(1):129-35. PubMed PMID: 6619105.

[4] Kitagishi K, Hiromi K. Binding between thermolysin and its specific inhibitor, N-phosphoryl-L-leucyl-L-tryptophan (PLT). J Biochem. 1986 Jan;99(1):191-7. PubMed PMID: 3957894.

[5] Kitagishi K, Hiromi K. Kinetics of binding between thermolysin and Streptomyces metalloprotease inhibitor, talopeptin (MKI). J Biochem. 1983 Jan;93(1):55-9. PubMed PMID: 6341370.

6: Kitagishi K, Hiromi K. Binding between thermolysin and its specific inhibitor, phosphoramidon. J Biochem. 1984 Feb;95(2):529-34. PubMed PMID: 6715312.7: Ichikawa S, Ohta M, Morioka H, Murao S. Blockage of ovulation in the explanted hamster ovary by a collagenase inhibitor. J Reprod Fertil. 1983 May;68(1):17-9. PubMed PMID: 6302251.8: Ichikawa S, Morioka H, Ohta M, Oda K, Murao S. Effect of various proteinase inhibitors on ovulation of explanted hamster ovaries. J Reprod Fertil. 1983 Jul;68(2):407-12. PubMed PMID: 6683319.9: Ichikawa S, Shibata T, Takehara Y, Tamada H, Oda K, Murao S. Effects of proteinase inhibitors on preimplantation embryos in the rat. J Reprod Fertil. 1985 Mar;73(2):385-90. PubMed PMID: 3838771.10: Tsuru D, Imajo S, Morikawa S, Yoshimoto T, Ishiguro M. Zinc protease of Bacillus subtilis var. amylosacchariticus: construction of a three-dimensional model and comparison with thermolysin. J Biochem. 1993 Jan;113(1):101-5. PubMed PMID: 8454566.1

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