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PNU-176798

NMR下載 COA and HPLC MSDS下載
names：
PNU-176798
CAS號(hào)：
428861-91-0
MDL Number：
MF(分子式)： C16H13FN4O3S MW(分子量)： 360.36
EINECS: Reaxys Number:
Pubchem ID:10338562 Brand:BIOFOUNT

PNU-176798（428861-91-0）是一種抗菌劑，靶向多種革蘭氏陽性和厭氧細(xì)菌中的蛋白質(zhì)合成。

貨品編碼	規(guī)格	純度	價(jià)格 (￥)	現(xiàn)價(jià)(￥)	特價(jià)(￥)	庫存描述	數(shù)量	總計(jì) (￥)
YZM000402-1mg	1mg	>97%	￥ 9155.00	￥ 9155.00		Backorder	- +	￥ 0.00

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中文別名	PNU-176798(428861-91-0)
英文別名	PNU-176798(428861-91-0),PNU176798,PNU 176798,N-[[(5S)-3-[4-(5-Cyano-1,3-thiazol-2-yl)-3-fluorophenyl]-2-oxo-1,3-oxazolidin-5-yl]methyl]acetamide
CAS號(hào)	428861-91-0
Inchi	InChI=1S/C16H13FN4O3S/c1-9(22)19-6-11-8-21(16(23)24-11)10-2-3-13(14(17)4-10)15-20-7-12(5-18)25-15/h2-4,7,11H,6,8H2,1H3,(H,19,22)/t11-/m0/s1
InchiKey	FGUCVLMMGZZQBB-NSHDSACASA-N
分子式 Formula	C16H13FN4O3S
分子量 Molecular Weight	360.36
溶解度Solubility
性狀	Solid
儲(chǔ)藏條件 Storage conditions	請(qǐng)根據(jù)產(chǎn)品建議的存儲(chǔ)條件進(jìn)行存儲(chǔ),Please store the product under the recommended condition sin the description.

PNU-176798(CAS:428861-91-0)實(shí)驗(yàn)注意事項(xiàng)：
1.實(shí)驗(yàn)前需戴好防護(hù)眼鏡，穿戴防護(hù)服和口罩，佩戴手套，避免與皮膚接觸。
2.實(shí)驗(yàn)過程中如遇到有毒或者刺激性物質(zhì)及有害物質(zhì)產(chǎn)生，必要時(shí)實(shí)驗(yàn)操作需要手套箱內(nèi)完成以免對(duì)實(shí)驗(yàn)人員造成傷害
3.實(shí)驗(yàn)后產(chǎn)生的廢棄物需分類存儲(chǔ)，并交于專業(yè)生物廢氣物處理公司處理，以免造成環(huán)境污染Experimental considerations:
1. Wear protective glasses, protective clothing and masks, gloves, and avoid contact with the skin during the experiment.
2. The waste generated after the experiment needs to be stored separately, and handed over to a professional biological waste gas treatment company to avoid environmental pollution.

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產(chǎn)品說明	PNU-176798(428861-91-0)是一種抗菌劑，可在廣泛的移殖性和厭氧性細(xì)菌中靶向蛋白質(zhì)合成。
Introduction	PNU-176798(428861-91-0)is an antimicrobial agent, targeting protein synthesis in a wide spectrum of gramositive and anaerobic bacteria.
Application1
Application2
Application3

警示圖
危險(xiǎn)性	warning
危險(xiǎn)性警示	Not available
安全聲明	H303吞入可能有害+H313皮膚接觸可能有害+H2413吸入可能對(duì)身體有害
安全防護(hù)	P264處理后徹底清洗+P280戴防護(hù)手套/穿防護(hù)服/戴防護(hù)眼罩/戴防護(hù)面具+P305如果進(jìn)入眼睛+P351用水小心沖洗幾分鐘+P338取出隱形眼鏡（如果有）并且易于操作,繼續(xù)沖洗+P337如果眼睛刺激持續(xù)+P2393獲得醫(yī)療建議/護(hù)理
備注	實(shí)驗(yàn)過程中防止吸入、食入，做好安全防護(hù)

Resistance to Linezolid Antimicrobial Drug Resistance 2009

1.Resistance to Linezolid
Abstract:The fi rst description of oxazolidinones as antibacterials was reported by researchers from the DuPont company in 1987. Compounds Dup-105 and DuP-721 (Fig. 1) were introduced as clinical candidates with good activity against Gram-positive pathogens, including methicillin-resistant Staphylococcus aureus, in an in vivo animal effi cacy model (1). These compounds demonstrated lethal toxicity in animal models and were not further developed (2). Researchers at Pharmacia (now Pfi zer) became interested in these molecules and began a chemistry/screening effort to improve the in vitro, in vivo, and safety profi les of oxazolidinones.

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